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Pathways Recommended: Stem Cell/Wnt Cell Cycle/DNA Damage
Results for "

ES cell

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

2

Fluorescent Dye

2

Biochemical Assay Reagents

2

Natural
Products

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N2335
    Coumestrol
    3 Publications Verification

    		 Estrogen Receptor/ERR Cancer
    Coumestrol, a phytoestrogen present in soybean products, exhibits activities against cancers, neurological disorders, and autoimmune diseases. It suppresses proliferation of ES2 cells with an IC50 of 50 μM.
    Coumestrol
  • HY-150047
    BK60106

    		Apoptosis Cancer
    BK60106 is a CD99 inhibitor that directly binds to the extracellular domain of CD99. BK60106 selectively kill Ewing sarcoma (ES) cells. BK60106 induces apoptosis in ES cells with less DNA damage .
    BK60106
  • HY-13626
    Spisulosine

    ES-285

    		 PKC Cancer
    Spisulosine (ES-285) is an antiproliferative (antitumoral) compound of marine origin. Spisulosine inhibits the growth of the prostate PC-3 and LNCaP cells through intracellular ceramide accumulation and PKCζ activation .
    Spisulosine
  • HY-13626S
    Spisulosine-d3

    		Isotope-Labeled Compounds PKC Cancer
    Spisulosine-d3 is deuterium labeled Spisulosine. Spisulosine (ES-285) is an antiproliferative (antitumoral) compound of marine origin. Spisulosine inhibits the growth of the prostate PC-3 and LNCaP cells through intracellular ceramide accumulation and PKC
    Spisulosine-d3
  • HY-136870
    Kyoto probe 1

    		Fluorescent Dye Others
    Kyoto probe 1 is a hiPSCs fluorescent probe. Kyoto probe 1 rapidly distinguishes between human ES/iPS (hES/hiPS) cells and differentiated cells. Kyoto probe 1 is primarily explained by the distinct expression patterns of ATP-binding cassette (ABC) transporters by hiPS cells and differentiated cells .
    Kyoto probe 1
  • HY-112483
    QX77
    3 Publications Verification

    		 Autophagy Cancer
    QX77 is a chaperone-mediated autophagy (CMA) activator and upregulates LAMP2A expression in vitro. QX77 induces Rab11 upregulation, rescues Rab11 down-regulation and trafficking deficiency in cystinotic cells . QX77 can impede self-renewal and promote differentiation of ES cells .
    QX77
  • HY-160715
    BNT411

    		Toll-like Receptor (TLR) Cancer
    BNT411 is a selective TLR7 agonist that can induce the release of IFNa both in vivo and in vitro. BNT411 has anticancer activity and can be used in cancer research, including non-small cell lung cancer, pancreatic cancer, and untreated extensive-stage small cell lung cancer (ES-SCLC) .
    BNT411
  • HY-120821
    Endosidin-2

    ES2

    		 Others Others
    Endosidin2 (ES2) binds to the exocyst component of 70 kDa (EXO70) subunit of the exocyst complex with a Kd of 253 μM. Endosidin2 inhibits exocytosis and endosomal recycling in both plant and human cells and enhances plant vacuolar trafficking. Endosidin2 is a valuable new tool for the study of exocytosis .
    Endosidin-2
  • HY-10182
    Laduviglusib
    Maximum Cited Publications
    141 Publications Verification

    CHIR-99021; CT99021

    		 Organoid GSK-3 Wnt β-catenin Autophagy Metabolic Disease Cancer
    Laduviglusib (CHIR-99021) is a potent, selective and orally active GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib enhances mouse and human embryonic stem cells self-renewal. Laduviglusib induces autophagy .
    Laduviglusib
  • HY-10182C
    Laduviglusib dihydrochloride

    CHIR-99021 dihydrochloride; CT99021 dihydrochloride

    		 GSK-3 β-catenin Wnt Metabolic Disease Cancer
    Laduviglusib;CHIR 99021;CHIR99021;CHIR-99021;CT99021;CT 99021;CT-99021
    Laduviglusib dihydrochloride
  • HY-10182G
    Laduviglusib

    CHIR-99021; CT99021

    		 GSK-3 Wnt β-catenin Autophagy Metabolic Disease Cancer
    Laduviglusib (CHIR-99021) (GMP) is Laduviglusib (HY-10182) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Laduviglusib is a potent, orally active and selective GSK-3α/β inhibitor.
    Laduviglusib
  • HY-14649G
    Retinoic acid

    Vitamin A acid; all-trans-Retinoic acid; ATRA

    		 RAR/RXR Cancer
    Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors .
    Retinoic acid

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